Task Force on Clinical (drug) Trials

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Task Force on Clinical (drug) Trials

Vision and mission of the Task Force

Vision of the task force:

Treatment aimed at improving the long-term outlook of children with heart disease requires the development of adequate drug treatment for common problems in these, including:

  • neurodevelopmental problems
  • impaired exercise tolerance
  • circulatory failure
  • cardiac arrhythmias

Mission of the task force:

The task force on clinical drug trials within the AEPC is dedicated to:

  • Provide the paediatric cardiology platform for clinical drug research
  • Contribute to improve , generalize and harmonize existing good practice
  • Improve trial design
  • Consistent delivery of high quality data
  • Integrate perspectives / needs of children and their families’ into the process
  • For this purpose we join forces with patients, scientists from adjacent fields, public funders, pharma industry and regulators

Board of the task force

Willem helbing

Prof Willem Helbing, MD, PhD


Erasmus MC – Sophia children’s hospital
Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Telephone: +31107036264
E-mail: w.a.helbing@erasmusmc.nl
Liason to C4C network and EnprEMA


Christoph Male, MD, MSc


Associate Professor of Paediatrics
Dept. of Paediatrics, Medical University of Vienna
Waehringer Guertel 18-20
Telephone: +43-1-40400-21100 or 32320
Fax: +43-1-40400-31541
E-mail: christoph.male@meduniwien.ac.at
Liason to C4C network and EnprEMA

Yogen Singh

Yogen Singh, MD, FRCPCH


Consultant in Pediatric Cardiology and Neonatology
Addenbrooke's Hospital, Box 402
Cambridge University Hospitals, Biomedical Campus
Cambridge, United Kingdom, CB2 0QQ
Telephone: +44 1223 217985
E-mail: Yogen.Singh@nhs.net or drsinghy@gmail.com

Damien Bonnet

Prof Damien Bonnet


Unité Médico-Chirurgicale de Cardiologie Congénitale et Pédiatrique
Centre de référence Malformations
Cardiaques Congénitales Complexes - M3C
Hôpital Necker Enfants Malades, APHP
Université Paris Descartes, Sorbonne Paris Cité
149 rue de Sèvres, 75015 Paris, France
Telephone: + 33 1 44 49 43 44 (assistant); + 33 1 44 49 43 49 (office)
Fax: + 33 1 44 49 43 40
E-mail: damien.bonnet1@gmail.com
Liason to WG Pulmonary Hypertension, Heart Failure and Transplantation


Prof Sylvie di Filippo


Pediatric & Fetal Cardiology & Adult
Congenital Heart Disease, Cardiovascular Hospital Louis Pradel, Claude Bernard University Lyon-1
28 Av. Doyen Lepine, 69677 Lyon, France
Telephone: +33 4 72357389
Fax: +33 4 72357049
E-mail: sylvie.di-filippo@chu-lyon.fr
Liason to AEPC council


Prof Daniel de Wolf


Department of Pediatric Cardiology, Ghent University Hospital (UZ Gent)
De Pintelaan 195, 9000 Gent, Belgium
Telephone: +32-9-3322464
Fax: +33 4 72357049
E-mail: daniel.dewolf@uzgent.be
Liason to WG Interventional cardiology


Juha-Matti Happonen


Hospital for Children and Adolescents University of Helsinki
P.O.Box 281
Stenbäckinkatu 11
FIN-00029 Helsinki
Liason to WG Cardiac Dysrhythmias and Electrophysiology

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